Pharmaceutical preparations containing one or more compounds which allosterically modify hemoglobin to affect its oxygen carrying capacity, where the compounds are dispersed or dissolved in a carrier fluid, gel, ointment or matrix, where the preparations are used in a wide variety of therapies, namely, oncology, anti-neoplast treatment, blood storage, blood restoration, and are used for treating a wide variety of disorders, namely, wound healing, ischemia, hypoxia, and hypothermia