Surgical and medical apparatus and instruments for use in general, ear, nose, and throat, orthopedic, neurosurgery, plastic, and cardiovascular surgery; sutures; drug delivery systems, namely, viscosupplementation therapies, inflammation management, pain management therapies, orthopedic joint implants; implantable devices for delivery of therapeutics including viscosupplementation therapies, and localized disease management in combination with bioactive compound devices for intra-articular injections