Pharmaceutical preparations, including pharmaceutical preparations for the treatment and prevention of lipoatrophy, lipodystrophy, hypothalamic amenorrhea, leptin deficiency, metabolic disorders, endocrine conditions and disorders, diabetes, hepatomegaly, hormonal diseases and disorders, obesity, eating disorders, cardiovascular diseases and disorders, gastrointestinal disorders, immunological disorders, inflammation and inflammatory diseases, neurological disorders, psychiatric disorders, pain, peripheral nervous system diseases and disorders, reproductive disorders, sexual dysfunction, urological disorders