Pharmaceutical and biological preparations for treating tenosynovial giant cell tumor (TGCT), giant cell tumor of the tendon sheath (GCT-TS), and pigmented villonodular synovitis (PVNS); Pharmaceutical and biological preparations for use in orthopedics, rheumatology, oncology, neurology, immunology, and hematology; Pharmaceutical and biological preparations for preventing, diagnosing, treating and managing diseases, disorders, and conditions affecting the musculoskeletal system, central nervous system, immune system, and blood; Pharmaceutical and biological preparations for treating tumors, sarcomas, tenosynovial giant cell tumors, graft versus host disease (GVHD), Parkinson's disease, Alzheimer's disease, and Amyotrophic Lateral Sclerosis (ALS); Therapeutic agents, namely, kinase inhibitors