Pharmaceutical preparations containing one or more compounds which allosterically modify hemoglobin to affect its oxygen carrying capacity where the compounds are dispersed or dissolved in a carrier fluid, gel, ointment or matrix where the preparations are used in a wide variety of therapies, namely, oncology, anti-neoplast treatment, blood storage, blood restoration and are used for treating a wide variety of disorders, namely wound healing, ischemia, hypoxia and hypothermia