Pharmaceutical formulations and preparations to treat acute and chronic health conditions related to gastrointestinal, inflammatory, metabolic, endocrine, immunological, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, oncological, hepatological, respiratory, neurological, psychiatric, dermatological, and viral diseases and disorders; pharmaceutical compositions in liquid form, namely, liquid compositions containing protease inhibitors, to treat health conditions, diseases, and disorders related to the gastrointestinal tract, gastrointestinal permeability, the gastrointestinal epithelial barrier, gastrointestinal inflammation, the gastrointestinal immune system, the microbiome, and the gut-brain axis; pharmaceutical formulations and preparations to treat or prevent surgical complications and post-surgical complications; pharmaceutical formulations and preparations to treat or prevent shock, namely, acute shock, cardiogenic shock, septic shock and hemorrhagic shock; pharmaceutical formulations and preparations to treat or prevent gastrointestinal tract injuries, ileus, and adhesions; pharmaceutical formulations and preparations to treat or prevent multi-organ failure; pharmaceutical formulations and preparations to treat or prevent health conditions, diseases, and disorders related to intestinal permeability, the microbiome, and the gut-brain axis.